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Caine series Home ->> Caine series
 
Tetracaine HCl
Time£º2018-7-20 15:04:21¡¡Page view£º280

quick details:

product name tetracaine hydrochloride/ tetracaine hcl
cas 136-47-0
mf c15h25cln2o2
mw 300.82
einecs 205-248-5
categories api intermediates;sodium channel;amines;aromatics;intermediates & fine chemicals;pharmaceuticals;pharmaceutical intermediate;pontocaine;local anesthetic
appearance pure white crystalline powder
assay 99.8%min
mp 149¡ãc
standard usp/bp
package aluminum foil bag inside+ carton box outside;1kg/bag,25kg/drum/ or discreetly disguised packings


product application:


a- for block anesthesia and epidural anesthesia.
b- also used for ventricular arrhythmias caused by myocardial infarction, digitalism, glucantime poisoning, surgery and so on. such as ventricular tachycardia, frequent ventricular premature beat, ventricular fibrillation.
c- as painkillers of injection in the medicament.
d- also used in suppository and ointment preparation, etc.


coa:

test items specification test results
appearance fine, white, crystalline, odorless powder confirm
identification abc in pass confirm
solubility very soluble in water, soluble in alcohol; insoluble in ether and benzene confirm
usp reference standards usp tetracaine hydrochloride rs. usp endotoxin rs. confirm
melting point 145~150 degree 146.0~147.5
degree
chromatographic purity in pass confirm
related substance not more than the reference solution 0.05% confirm
heavy metals ¡Ü10ppm confirm
ph 4.5-6.5 5.8
residue on ignition ¡Ü0.10% 0.05%
loss on drying ¡Ü 0.5% 0.19%
assay 98.0 -101.0% 100.1%
conclusion confirms usp 32
 
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